DOWNREGULATION OF MICRORNA-145 CAUSED BY HEPATITIS B VIRUS X PROTEIN PROMOTES EXPRESSION OF CUL5 AND CONTRIBUTES TO PATHOGENESIS OF HEPATITIS B VIRUS-ASSOCIATED HEPATOCELLULAR CARCINOMA

Downregulation of MicroRNA-145 Caused by Hepatitis B Virus X Protein Promotes Expression of CUL5 and Contributes to Pathogenesis of Hepatitis B Virus-Associated Hepatocellular Carcinoma

Background: Hepatitis B viral infection-induced hepatocellular carcinoma (HCC) is a major threat to human health in China.Hepatitis B virus X protein (HBX), an HBV protein, has been reported to be involved in regulating the cellular activities of the host cells Laundry Storage Basket and is responsible for HCC oncogenesis.Methods and Results: In th

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Autologous miniature punch grafting in stable vitiligo

Autologous miniature punch grafting with certain modifications was taken up in 54 sites in 30 patients with stable vitiligo for 6 months or more.The modifications were: (a) use of same sized disposable punches for both donor and recipient areas except climber motor over convex body surfaces, (b) use of Castraviejo′s scissors for harvesting d

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FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress

Abstract Homologous recombination (HR) plays critical roles in repairing lesions Lip Makeup that arise during DNA replication and is thus essential for viability.RAD51 plays important roles during replication and HR, however, how RAD51 is regulated downstream of nucleofilament formation and how the varied RAD51 functions are regulated is not clear.

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Surgical treatment of a mandibular condyle fracture

The condylar region is the most frequent anatomical site for mandibular fractures in children.Most surgeons opt for functional treatment which is not satisfactory in the long term because of Granola the appearance of facial asymmetry and TMJ dysfunction, hence the interest in surgical management of displaced condylar fractures.In this article, we w

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